Currents were normalized to the maximum value after sensitization

(F) [Ca2+]i increases elicited by different concentrations of 2 APB measured by Fluo 4 in TRPV3 (upper) and pcDNA3 transfected cells (lower). The extracellular pH was 7.4 initially and subsequently lowered to 5.6 without a change in 2 APB concentration.

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